When Cannabis sativa is consumed, the active THC compound is carried to the brain by the blood stream. In the brain, it binds with the cannabinoid receptors of the nerve cells and thereby brings about a change in their activities. These cannabinoid receptors are mostly found in those regions of the brain, which control memory, thought, sensation of pleasure, perception and concentration. By altering the activities of the neurons, Cannabis sativa adversely affects memory, concentration, thinking capacity and creates a distorted perception.
THC also affects the production and release of the neurotransmitter dopamine, and hence, stimulates certain regions of the brain, which produce a pleasurable excitement. Therefore, individuals using Cannabis sativa, feel a sense of elated happiness. It has been observed that the effects produced by the intake of Cannabis sativa last for several days or weeks. After the initial stage of feeling high or elated, the abuser often feels depressed or sleepy. Sometimes, Cannabis sativa abuse can also produce anxiety or panic, along with a sense of fear and distrust.
Regular use of Cannabis sativa naturally leads to an addiction. Sudden withdrawal, after using it for a long time, can cause irritability, loss of appetite, sleep deprivation, anxiety, etc. Some researches have suggested a link between Cannabis sativa and anxiety, depression, suicidal tendendencies and even schizophrenia. As far as a possible association between Cannabis sativa use and mental illness is concerned, enough supportive evidence is not available. However, regular use at an early age is presumed to put a person at a higher risk of suffering from mental illnesses. Intake of a high dose of Cannabis sativa can cause psychotic reactions like hallucinations and delusions.
